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An automatic computer vision pipeline for the in-line monitoring of freeze-drying processes

Infrared imaging sensors were proposed in the past years for the real-time monitoring and control... of the Vacuum Freeze Drying (VFD) process. In order to extract reliable, real-time, and quantitative features from images collected by these sensors, a robust and automated image processing pipeline is required.

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Method development and analysis of the water content of the maximally freeze concentrated solution suitable for protein lyophilisation

During freeze-drying of a liquid formulation, a freeze-concentrate is formed in the first phase, ...the freezing step.Understanding the composition of the maximally freeze concentrated solution can help to judge the process stability of biopharmaceuticals during lyophilisation.

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