Sensitivity Analysis of a Neural Network based Avionic System by Simulated Fault and Noise Injection
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Autonomous taxi operations: Algorithma for the solution of the routing problem
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Process intensification and process control in freeze-drying
Widespread use of advanced process control allows reduction of costs, by reducing drying time and... energy consumption. The “control of the freezing stage” (by forced nucleation) also appears to be beneficial to process intensification, as it can impact the product structure and modify the product resistance to mass transfer.
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Image segmentation and 3D reconstruction for improved prediction of the sublimation rate during freeze drying
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Preparation of bio-functional textiles by surface functionalization of cellulose fabrics with caffeine loaded nanoparticles
In recent years transdermal drug delivery has aroused significant interest as a sustained and non...-invasive way of administering active substances. The development of nanotechnology allowed the development of novel pharmaceutical formulations overcoming skin barrier.
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Vacuum Induced Surface Freezing as an effective method for improved inter- and intra-vial product homogeneity
The stochastic nature of nucleation makes it difficult to control batch homogeneity in convention...al freezing, and this lack of control is in contrast with the current emphasis on Quality by Design.
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Computational Fluid Dynamics data for improving freeze-dryers design
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Use of Computational Fluid Dynamics for improving freeze-dryers design and understanding. Part 1: Modelling the lyophilisation chamber
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Overcoming the limits of flash nanoprecipitation: effective loading of hydrophilic drug into polymeric nanoparticles with controlled structure
Flash nanoprecipitation (FNP) is a widely used technique to prepare particulate carriers based on... various polymers, and it was proven to be a promising technology for the industrial production of drug loaded nanoparticles.
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Process Analytical Technology for monitoring pharmaceuticals freeze drying - A Comprehensive Review
The goal of this paper is to review the available process analytical technology tools for monitor...ing the batch freeze-drying process for pharmaceuticals.
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